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The kidneys make urine by filtering the blood. Normally no protein passes into the urine when the blood is filtered, because protein in the blood is too large to pass through the tiny holes in the kidney filters. However, the filter can be damaged in kidney disease, so that protein can pass into the urine.

Water retention in the body is most commonly caused by heart disease, so the first thing a doctor will check is the heart. Sometimes heart tests seem to delay the diagnosis of a kidney condition. This is often understandable because heart disease is important and much commoner than kidney disease.

The main clue to nephrotic syndrome is protein in the urine. This can be detected by a simple ‘dipstick’ test on a small urine sample.

To make a firm diagnosis of the cause of nephrotic syndrome, it is usually necessary to perform a kidney biospy. This is the removal of a small fragment of kidney using a needle, so that the kidney can be examined under a microscope.


The underlying kidney disease may be treatable with drugs. The type of treatment depends on the cause. 

Fluid retention can be treated by reducing the amount of salt and water taken in your diet each day. Some cases also require drugs to make the kidneys produce more urine.

Blood clots can be treated with drugs to thin the blood. 

A high cholesterol level may be treated with dietary control (eating less fat), and in some cases with cholesterol lowering drugs.

Call  us at kingwood kidney associates 281-401-9540 to schedule your appointment to help diagnose and manage nephrotic syndrome. 

You can also schedule your appointment online using the booking tool on this page. Book your examination today.


Dr. Sowmya Puthalapattu Sowmya Puthalapattu, MD, or Dr. Sowmya as she’s known to patients, is an experienced board-certified nephrologist and internal medicine physician at Kingwood Kidney Associates, with offices in Kingwood and The Woodlands, Texas. Dedicated to providing her patients with comprehensive individualized care, Dr. Puthalapattu believes in the importance of active listening and having an open and creative clinical mind to provide the right care to meet her patients’ needs. She is faculty and Subspeciality education coordinator for Nephrology at IM GME program HCA Kingwood . Her areas of specialty include chronic kidney disease, end-stage renal disease, hyponatremia, and high blood pressure. A resident of The Woodlands, Texas, Dr. Puthalapattu spends her free time with her husband and two children. Her favorite activities include hiking and traveling.

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